Comparative Analysis of the Human Dystrophin and Utrophin Gene Structures
نویسندگان
چکیده
منابع مشابه
Comparative analysis of the human dystrophin and utrophin gene structures.
We present analysis of intronic sequences in the human DMD and UTRN genes. In both genes accumulation of repeated elements could account for intron expansion. Out-of-frame rod-domain exons have stronger splice sites and are separated by significantly longer introns as compared to in-frame exons. These features are unique for the two homologs and not shared by other spectrin superfamily genes.
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ژورنال
عنوان ژورنال: Genetics
سال: 2002
ISSN: 1943-2631
DOI: 10.1093/genetics/160.2.793